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Read more at: Single particle trajectories reveal active endoplasmic reticulum luminal flow

Single particle trajectories reveal active endoplasmic reticulum luminal flow

Holcman D, Parutto P, Chambers JE, et al. "Single particle trajectories reveal active endoplasmic reticulum luminal flow. " Nat. Cell Biol. (2018), 20(10):1118. Abstract The endoplasmic reticulum (ER), a network of membranous sheets and pipes, supports functions encompassing biogenesis of secretory...


Read more at: FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-p Interactions

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-p Interactions

S Qamar, GZ Wang, SJ Randle, et al. "FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions." Cell . (2018), 173(3):720–734. Abstract Reversible phase separation underpins the role of FUS in ribonucleoprotein granules and other membrane-free...


Read more at: Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure

Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure

Laine RF, Goodfellow G , Young LJ, Travers J, Carroll D, Dibben O, Bright H & Kaminski CF. "Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure." eLife (2018), 7. Abstract Optical super-resolution...


Read more at: Scalable integration of nano-, and microfluidics with hybrid two-photon lithography

Scalable integration of nano-, and microfluidics with hybrid two-photon lithography

Vanderpoorten O, Peter Q, Challa PK, Keyser UF, Baumberg J, Kaminski CF & Knowles TPJ, " Scalable integration of nano-, and microfluidics with hybrid two-photon lithography" , Microsystems & Nanoengineering (2019) 5(1):40 DOI | pdf Abstract Nanofluidic devices have great potential for...


Read more at: Super-condenser enables labelfree nanoscopy

Super-condenser enables labelfree nanoscopy

Ströhl F, Opstad IS, Tinguely JC, Dullo FT, Mela I, Osterrieth JWM, Ahluwalia BS, Kaminski CF , " Super-condenser enables labelfree nanoscopy" , Opt. Express (2019) 27:25280-25292 DOI: 10.1364/OE.27.025280 | pdf Abstract Labelfree nanoscopy encompasses optical imaging with resolution in the 100 nm...


Read more at: Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans

Huang C, Wagner-Valladolid S, Stephens AD, Jung R, Poudel C, Sinnige T, Lechler MC, Schlörit N, Lu M, Laine RF, Michel CH, Vendruscolo M, Kaminski CF, Kaminski Schirrle GS, David DC. "Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans...


Read more at: Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α‑Synuclein and Polyglutamine in Aging Caenorhabditis elegans

Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α‑Synuclein and Polyglutamine in Aging Caenorhabditis elegans

Lain R, Sinnige T, Ma KY, Haack AJ, Poudel C, Gaida P, Curry N, Perni M, Nollen EAA, Dobson CM, Vendruscolo M, Kaminski Schierle GS, Kaminski CF "Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α‑Synuclein and Polyglutamine in Aging Caenorhabditis elegans ." , ACS Chem. Biol...


Read more at: Opal-like Multicolor Appearance of Self-Assembled Photonic Array

Opal-like Multicolor Appearance of Self-Assembled Photonic Array

Arnon ZA, Pinotsi D, Schmidt M, et al. "Opal-like Multicolor Appearance of Self-Assembled Photonic Array. " ACS Appl. Mater. Interfaces. (2018), 10(24):20783–20789. DOI | pdf Abstract Molecular self-assembly of short peptide building blocks leads to the formation of various material architectures...


Read more at: Structural progression of amyloid- Arctic mutant aggregation in cells revealed by multiparametric imaging

Structural progression of amyloid- Arctic mutant aggregation in cells revealed by multiparametric imaging

Lu M, Williamson N, Mishra A, Michel CH, Kaminski Schierle GS, Tunnacliffe A, Kaminski CF "Structural progression of amyloid-β arctic mutant aggregation in cells revealed by multiparametric imaging" Journal of Biological Chemistry (2019), 294:1478-1487. DOI | pdf Abstract The 42-amino-acid β-...


Read more at: Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly

Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly

Lu M, Benetta L, young LJ, Smith EJ, Bates GP, Zaccone A, Kaminski Schierle GS, Tunnacliffe A, Kaminski CF "Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly." Journal of Biological Chemistry (2019), 249:257-268. DOI | pdf Abstract...