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Read more at: a-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?

a-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?

Lautenschläger J, Kaminski CF, Kaminski Schierle GS, "α-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?" , Trends in Cell Biology (2017), 27(7), 468-9. DOI: 10.1016/j.tcb.2017.02.002 | pdf Abstract α-Synuclein is known as a presynaptic protein that binds to small synaptic vesicles...


Read more at: A new online tool for visualization of volumetric data

A new online tool for visualization of volumetric data

Fantham M, Kaminski CF, "A new online tool for visualization of volumetric data" , Nature Photonics (2017), 11, 69. DOI: 10.1038/nphoton.2016.273 | pdf | Supp info 1 | Supp info 2 | Supp info 3 Abstract New popular microscopy techniques such as structured illumination microscopy (SIM), selective...


Read more at: Quantitative affinity determination by fluorescence anisotropy measurements of individual nanoliter droplets

Quantitative affinity determination by fluorescence anisotropy measurements of individual nanoliter droplets

Gielen F, Butz M, Rees EJ, Erdelyi M, Moschetti T, Hyvönen M, Edel JB, Kaminski CF, Hollfelder F, "Quantitative affinity determination by fluorescence anisotropy measurements of individual nanoliter droplets" , Anal. Chem. (2017), 89(2), 1092-1101. DOI: 10.1021/acs.analchem.6b02528 | pdf | Supp...


Read more at: Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter

Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter

Nespovitaya N, Mahou P, Laine RF, Kaminski Schierle GS, Kaminski CF, "Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter" , Chem. Commun. (2017), 53, 1273-1276. DOI: 10.1039/C6CC09770G | pdf | Supplementary info Abstract The aggregation...


Read more at: Investigating state restriction in fluorescent protein FRET using time-resolved fluorescence and anisotropy

Investigating state restriction in fluorescent protein FRET using time-resolved fluorescence and anisotropy

Blacker TS, Chen WY, Avezov E, Marsh RJ, Duchen MR, Kaminski CF, Bain AJ, "Investigating state restriction in fluorescent protein FRET using time-resolved fluorescence and anisotropy" , J. Phys. Chem. C (2017), 121(3), 1507-1514. DOI: 10.1021/acs.jpcc.6b11235 | pdf Abstract Most fluorescent...


Read more at: Fluorescence self-quenching from reporter dyes informs on the structural properties of amyloid clusters formed in vitro and in cells

Fluorescence self-quenching from reporter dyes informs on the structural properties of amyloid clusters formed in vitro and in cells

Chen WY, Young LJ, Lu M, Zaccone A, Strohl F, Yu N, Kaminski Schierle GS, Kaminski CF, "Fluorescence self-quenching from reporter dyes informs on the structural properties of amyloid clusters formed in vitro and in cells" , Nano Lett. (2017), 17(1), 143-149. DOI: 10.1021/acs.nanolett.6b03686 | pdf...


Read more at: Tomographic absorption spectroscopy for the study of gas dynamics and reactive flows

Tomographic absorption spectroscopy for the study of gas dynamics and reactive flows

Cai W, Kaminski CF, "Tomographic absorption spectroscopy for the study of gas dynamics and reactive flows" , PECS. (2017), 59, 1-31. DOI: 10.1016/j.pecs.2016.11.002 | pdf Abstract Optical imaging techniques are ubiquitous for the resolution of non-uniformities in gas flows. Planar imaging...


Read more at: De novo design of a biologically active amyloid

De novo design of a biologically active amyloid

Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet...


Read more at: Structural basis of synaptic vesicle assembly promoted by a-synuclein

Structural basis of synaptic vesicle assembly promoted by a-synuclein

Fusco G, Pape T, Stephens AD, Mahou P, Costa A, Kaminski CF, Kaminski Schierle GS, Vendruscolo M, Veglia G, Dobson CM, De Simone A "Structural basis of synaptic vesicle assembly promoted by α-synuclein" , Nature Communications. (2016), 7: 12563. DOI: 10.1038/ncomms12563 | pdf Abstract α-synuclein (...


Read more at: From single-molecule spectroscopy to super-resolution imaging of the neuron: a review

From single-molecule spectroscopy to super-resolution imaging of the neuron: a review

Laine RF, Kaminski Schierle GS, van de Linde S, Kaminski CF, "From single-molecule spectroscopy to super-resolution imaging of the neuron: a review" , Methods Appl. Fluoresc. (2016), 4: 022004. DOI: 10.1088/2050-6120/4/2/022004 | pdf Abstract For more than 20 years, single-molecule spectroscopy has...