Dr Amir Rahmani

Amir is a PDRA in the Department of Chemical Engineering and Biotechnology (CEB) at the University of Cambridge, working in close collaboration with the British Antarctic Survey (BAS). His research focuses on developing advanced tools for live-cell super-resolution imaging of biological dynamics at sub-zero temperatures. He is jointly supervised by Prof. Clemens Kaminski (CEB) and Prof. Melody Clark (BAS).

Biography

Amir holds a PhD in Physics, where he developed a single-molecule imaging flow cytometry system to quantify individual molecules on cell membrane. His doctoral research was supported by the EPSRC Doctoral Training Partnership Studentship.

Before undertaking his PhD, Amir gained hands-on experience in super-resolution microscopy at leading research institutions, including the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Photonic Sciences (ICFO) in Barcelona.

Publications

Key publications:

[1] Marty AP,* Rahmani A,* van Tartwijk F, Peck LS, Clark MS, Kaminski CF. "Challenges and limitations for live cell imaging in extreme cold". Meth. App. in Fluor. (2026). doi: 10.1088/2050-6120/ae8c12

[2] van Tartwijk F,* Marty AP,* Rahmani A, Jia Y, Ward EN, Hussain I, Peck LS, Kaminski CF, Clark MS. "Antarctic fish cell cultures show adaptation of organelle morphology and dynamics to extreme cold", bioRxiv 2026.04. 24.720652, (2026). doi: 10.64898/2026.04.24.720652

[3] Rahmani A, Christie M, Truesdale A, Thorne J, Ponjavic A. "Single-molecule flow cytometry". bioRxiv 2025.08. 26.672174 (2025) doi: 10.1101/2025.08.26.672174

[4] Nguyen TD, Rahmani A, Ponjavic A, Millett-Sikking A, Fiolka R. "Active remote focus stabilization in oblique plane microscopy". Biomedical Optics Express, Vol. 16, Issue 3, pp. 1216-1224, (2025). doi: 10.1364/BOE.553545

[5] Rahmani A, Cox T, Achary ATA, Ponjavic A. "Astigmatism-based active focus stabilisation with universal objective lens compatibility, extended operating range and nanometer precision". Optics Express, Vol. 32, Issue 8, pp. 13331-13341 (2024). doi: 10.1364/OE.520845

Subject:

Microscopy