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Publications Collection

Our group's publications

Total internal reflection fluorescence anisotropy imaging microscopy: setup, calibration, and data processing for protein polymerization measurements in living cells
Nanoscale click-reactive scaffolds from peptide self-assembly
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
Speed limits of structured illumination microscopy
Temperature treatment of highly porous zirconium-containing metal–organic frameworks extends drug delivery release
Correlative STED and atomic force microscopy on live astrocytes reveals plasticity of cytoskeletal structure and membrane physical properties during polarized migration
Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons
TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2
Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
a-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?
Optical Imaging of Protein Aggregation Reactions In Vitro and in Cells
First Person Bioimage: An Online Tool for Presentation and Publication of Volumetric Data
A new online tool for visualization of volumetric data
Super-resolution imaging of alpha-synuclein polymorphisms and their potential role in neurodegeneration
Quantitative affinity determination by fluorescence anisotropy measurements of individual nanoliter droplets
Investigating state restriction in fluorescent protein FRET using time-resolved fluorescence and anisotropy
Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter
Fluorescence self-quenching from reporter dyes informs on the structural properties of amyloid clusters formed in vitro and in cells
Tomographic absorption spectroscopy for the study of gas dynamics and reactive flows
De novo design of a biologically active amyloid
Structural basis of synaptic vesicle assembly promoted by a-synuclein
From single-molecule spectroscopy to super-resolution imaging of the neuron: a review
Introduction to ‘Sensors in technology and nature’
Frontiers in structured illumination microscopy
Probing amyloid protein aggregation with optical superresolution methods: from the test tube to models of disease
From single-molecule spectroscopy to super-resolution imaging of the neuron: a review
Development of an open technology sensor suite for assisted living— a student-led research project
A guide to structured illumination TIRF microscopy at high speed with multiple colors
Proton transfer and structure-specific fluorescence in hydrogen bond-rich protein structures
In situ visualization of block copolymer self-assembly in organic media by super-resolution fluorescence microscopy

Building bespoke high-resolution imaging platforms for research into neurodegeneration.

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Single molecule translation imaging

Nov 15, 2017

Single molecule translation imaging, SMTI, is a novel technique development by the Laser Analytics group to measure the rate and spatial distribution of protein synthesis [1,2]. Together with scientists form the Department of Physiology and Development of the University of Cambridge, we study the processes underlying neurodevelopment and the formation of neuronal networks in vivo.

The LAG offers best wishes to Dr. Romain Laine on his next adventure

Oct 30, 2017

The LAG says farewell to Dr. Romain Laine as he moves to his new position as a research fellow in Ricardo Henriques' lab at University College London.

LAG and MNG members participate in the 2017 Chariots of Fire relay race

Sep 18, 2017

Laser Analytics Group members Nathan Curry and Pedro Vallejo Ramirez, along with Molecular Neuroscience Group members Amberley Stephens, Nadya Nespovitaya, Ajay Mishra, and Miranda Robbins participated in the annual Chariots of Fire relay race.

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