Research

The central theme of our work is the development and application of modern laser spectroscopy and imaging methods to elucidate details and dynamics of chemical processes. Below you find summaries of, and links to, key research projects currently going on in the group.

Dynamic live cell imaging at sub-zero temperatures In a groundbreaking collaboration between the Department of Chemical Engineering and Biotechnology (CEB) and the British Antarctic Survey (BAS), we are pioneering dynamic live cell imaging at sub-zero temperatures. One of just 36 projects funded by the UKRI cross research council pilot scheme, this initiative aims to develop advanced microscopy capable of observing living cells at cold. By bridging biology, physics, engineering, and chemistry, the project promises transformative insights into how life adapts in the extreme environments.
Molecular Mechanisms of disease We use a range of advanced biological and biophysical methods to probe the molecular chemistry of disease in live cells and in animal models.  Currently a major focus is on the study of protein misfolding and aggregation in neurodegeneration.
Microscopy Development We perform both experimental and theoretical work to optimize speed, resolution, and sensitivity for applications ranging from single molecule biophysics to whole organism imaging.