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The LAG offers best wishes to Dr. Romain Laine on his next adventure

The LAG says farewell to Dr. Romain Laine as he moves to his new position as a research fellow in Ricardo Henriques' lab at University College London.

The LAG is most grateful for the absolutely fantastic work Dr. Romain Laine has done in the past 4 years as a post-doctoral researcher in the group. Romain was involved in numerous collaborations, published multiple high impact papers (see list below), and was a mentor and guide for many PhD students during this time in the group. Romain designed, built, and operated a series of microscopes in the lab, including a time-gated fluorescence lifetime microscope (TG-FLIM) and a TIRF( total internal reflection) microscope with dSTORM (stochastic optical reconstruction microscopy) capabilities. Romain was also involved in projects with structured illumination microscopy (SIM), machine learning, optical projection tomography, and time-correlated single photon counting (TCSPC). On top of the research work, Romain also organized the day-to-day running of the lab, organized practicals for project or master's students, and participated actively in the group's social and sports events. 

We had a group dinner at a local pub to wish him well in his next journey as a research fellow in Ricardo Henriques' group at University College London (UCL). Outside the lab, Romain enjoys teaching music for capoeira and is a percussionist himself, so the group gave him a cajon (box-shaped percussion instrument) as a farewell present so he can continue jamming in London.  Thank you for your outstanding work! We will miss you dearly!

Some of the publications Romain was involved in during his years in the group are highlighted below: 


Wong HH-W, Lin J Q, Ströhl F, Roque CG, Cioni J-M, Cagnetta R, Turner-Bridger B, Laine R F, Harris WH, Kaminski CF, Holt CE (2017). "RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo" Neuron 95 (4) 852-868. DOI

Ströhl F, Lin JQ, Laine RF, Wong HH, Urbančič V, Cagnetta R, Holt CE, Kaminski CF, "Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons"Sci. Rep. (2017), 7, 709. DOI

Nespovitaya N, Mahou P, Laine RF, Kaminski Schierle GS, Kaminski CF, "Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter"Chem. Commun. (2017), 53, 1273-1276. DOI


Laine RF, Kaminski Schierle GS, van de Linde S, Kaminski CF, "From single-molecule spectroscopy to super-resolution imaging of the neuron: a review"Methods Appl. Fluoresc. (2016), 4: 022004. DOI

Pinotsi D, Michel CH, Buell AK, Laine RF, Mahou P, Dobson CM, Kaminski CF, Kaminski Schierle GS, "Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons" PNAS, (2016), 113 (14), 3815-3819. DOI

Albecka A, Laine RF, Janssen AFJ, Kaminski CF, Crump CM, "HSV-1 glycoproteins are delivered to virus assembly sites through dynamin-dependent endocytosis", Traffic (2016), 17: 21-39. DOI


Manners I, Boott CE, Laine RF,  Mahou P,  Finnegan JR,  Leitao EM,  Webb SED,  Kaminski CF, "In situ visualization of block copolymer self-assembly in organic media by super-resolution fluorescence microscopy"Chem. Eur. J. (2015), 21:18539–18542. DOI

Chen WY, Avezov E, Schlachter SC, Gielen F, Laine RF, Harding HP, Hollfelder F, Ron D and Kaminski CF, "A Method to Quantify FRET Stoichiometry with Phasor Plot Analysis and Acceptor Lifetime In-growth," Biophys. J. (2015), 108 (5), 2015, pp. 999-1002. DOI

Avezov E, Konno T, Zyryanova A, Chen WY, Laine R, Crespillo-Casado A, Melo E P, Ushiodo R, Nagata K, Kaminski CF, Harding HP, "Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum", BMC Biology (2015), 13:2. DOI

Laine R F. Albecka A, van de Linde S, Rees EJ, Crump CM, Kaminski CF, "Structural analysis of herpes simplex virus by optical super-resolution imaging"Nature Comms. (2015), 6:5980. DOI