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James Manton


I am an MRC Career Development Fellow at the MRC Laboratory of Molecular Biology, Cambridge. Previously, I did my PhD under the supervision of Eric Rees and was part of the EPSRC Centre for Doctoral Training in Sensor Technologies and Applications. Before this, I was a Research Assistant in Gregory Jefferis' lab at the MRC Laboratory of Molecular Biology for a year following my BA in Natural Sciences at Trinity College, University of Cambridge, to which I returned for my PhD.

Key Publications

James D. Manton, Yao Xiao, Robert D. Turner, Graham Christie, and Eric J. ReesELM: super-resolution analysis of wide-field images of fluorescent shell structures. Methods and Applications in Fluorescence (2018). In press.

Abhinaba Ghosh, James D. Manton, Amin R. Mustafa, Mudit Gupta, Alejandro Garcia, Eric J. Rees, and Graham Christie
. Proteins encoded by the gerP operon are localised to the inner coat in Bacillus cereus spores and are dependent on GerPA and SafA for assembly. Applied and Environmental Microbiology (2018). In press.

James D. Manton, and Eric J. Rees
. triSPIM: light sheet microscopy with isotropic super-resolutionOptics Letters 41, 4170–4173 (2016). doi: 10.1364/OL.41.004170.

Marta Costa, James D. Manton, Aaron D. Ostrovsky, Steffen Prohaska, and Gregory S.X.E. Jefferis. NBLAST: Rapid, sensitive comparison of neuronal structure and construction of neuron family databases. Neuron 91, 293–311 (2016). doi: 10.1016/j.neuron.2016.06.012.

James D. Manton, Josephine A.E. Hughes, Oliver Bonner, Omar A. Amjad, Philip Mair, Isabella Miele, Tiesheng Wang, Vitaly Levdik, Richard D. Hall, Géraldine Baekelandt, Fernando C. Vasconcellos, Oliver Hadeler, Tanya Hutter, and Clemens F. Kaminski. Development of an open technology suite for assisted living: a student-led research project. Interface Focus 6, 20160018 (2016). doi: 10.1098/rsfs.2016.0018.

Julia Manetsberger, James D. Manton, Miklos J. Erdelyi, Henry D. Rees, Graham Christie, and Eric J. Rees. Ellipsoid localisation microscopy infers the size and order of protein layers in Bacillus spore coats. Biophysical Journal 109, 2058–2066 (2015). doi: 10.1016/j.bpj.2015.09.023.

James D. Manton, Aaron D. Ostrovsky, Lea Goetz, Marta Costa, Torsten Rohlfing, and Gregory S.X.E. Jefferis. Combining genome-scale Drosophila 3D neuroanatomical data by bridging template brains. BioRxiv (2014). doi: 10.1101/006353.