Biography
I am a Research Associate in the group of Clemens Kaminski at the University of Cambridge where I work on virus-host cell interaction using advanced fluorescence imaging methods. Previously, I was awarded an individual fellowship by the German Research Foundation and investigated the dynamics of herpesvirus assembly and egress and related changes in host-cell morphology.
Before coming to Cambridge in March 2017, I was a postdoc in Tom Shimizu’s lab at the AMOLF institute in Amsterdam studying the organisation of chemotaxis receptors in E. coli. Previously, I completed my PhD in Chemistry under the supervision of Ulrich Kubitscheck at the University of Bonn, where I investigated the mechanisms of the action of antibiotics.
Publications
Bo Meng*, Pedro P. Vallejo Ramirez*, Katharina M. Scherer, Ezra Bruggeman, Julia C. Kenyon, Clemens F. Kaminski, Andrew M. Lever. Distinct domain requirements for EAP45 in HIV budding, late endosomal recruitment, and cytokinesis, bioRxiv 2020. https://doi.org/10.1101/2020.05.23.112607.
Luca Mascheroni*, Katharina M. Scherer*, Edward Ward, Oliver Dibben, Clemens F. Kaminski. Combining light sheet microscopy and expansion microscopy for fast 3D imaging of virus-infected cells with super-resolution, bioRxiv 2020. https://doi.org/10.1101/2020.04.10.035378.
Katharina M. Scherer, James D. Manton, Timothy Soh, Luca Mascheroni, Colin M. Crump, Clemens F. Kaminski. Spatiotemporal analysis of host cell modification during herpes simplex virus 1 replication, bioRxiv 2019. https://doi.org/10.1101/2019.12.22.872002.
Fabian Grein*, Anna Müller*, Katharina M. Scherer*, Xinliang Liu, Kevin C. Ludwig, Anna Klöckner, Manuel Strach, Hans-Georg Sahl, Ulrich Kubitscheck, Tanja Schneider. Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids, Nature Communications 2020, 11, 1455.
Christopher J. Rowlands, Florian Stroehl, Pedro P. V. Ramirez, Katharina M. Scherer, Clemens F. Kaminski. Flat-field super-resolution localization microscopy with a low-cost refractive beam-shaping element, Sci. Rep. 2018, 8:5630.
Jacopo Solari, Francois Anquez, Katharina M. Scherer, Thomas S. Shimizu. Bacterial chemoreceptor imaging at high spatiotemporal resolution using photoconvertible fluorescent proteins, Methods Mol Biol. 2018, 1729, 203-231.
Katharina M. Scherer, Jan-Hendrik Spille, Fabian Grein, Hans-Georg Sahl, Ulrich Kubitscheck. The lantibiotic nisin induces formation of large Lipid II aggregates causing membrane instability and vesicle budding, Biophys. J. 2015, 108, 1114-1124.
Jan-Hendrik Spille, Tim P. Kaminski, Katharina Scherer, Jennifer S. Rinne, Alexander Heckel, Ulrich Kubitscheck. Extended, sensitive and fast 3D-tracking of single molecules and RNA particles in living tissue, Nucleic Acids Res. 2014, pii: gku1194.
Katharina Scherer, Imke Wiedemann, Corinna Ciobanasu, Hans-Georg Sahl, Ulrich Kubitscheck, Aggregates of nisin with various bactoprenol-containing cell wall precursors differ in size and membrane permeation capacity, Biochim. Biophys. Acta 2013, 1828, 2628-2636.
